Moufied Mansour is the brother of Ahmed Subhy Mansour, a prominent Quranist scholar and founder of the International Quranic Center (IQC). A physician by profession, he has supported the family's involvement in the Quranist movement, which interprets Islam strictly based on the Quran while rejecting hadiths and sunna. Originally from Egypt, Moufied relocated to the United States along with his brother, where they have promoted reformist Islamic ideas amid controversy, including persecution in Egypt during the 1980s for their views.