Marianne Ginther Gingrich is an American health care executive and former environmental lobbyist, best known as the second wife of former U.S. House Speaker Newt Gingrich; the couple was married from 1981 to 1999. She was born and raised in Leetonia, Ohio, one of four children of Harry Ginther, the late mayor of Leetonia. As a student at Kent State University, she experienced the 1970 anti-war protest in which four students were killed by the National Guard. She pursued higher education, potentially including a Bachelor's degree in Business Administration from the University of Illinois.

Marianne began her career as a registered nurse before transitioning into lobbying and executive roles in healthcare and environmental advocacy. In 1995, she was hired as vice president of the Israel Export Development Corporation (IEDC), an IASPS-affiliated organization, highlighting her involvement in international business and influence networks. Her professional work has intersected government policy, healthcare, and international trade, with connections to political and business circles, particularly in Washington, D.C. Following her divorce from Gingrich, she continued working in healthcare executive roles while maintaining a relatively low public profile.