Marie Villafaña, also known as A. Marie Villafaña or Ann Marie C. Villafaña, is a former Assistant U.S. Attorney in the Southern District of Florida. She served as the lead federal prosecutor in the 2008 Jeffrey Epstein case, aggressively pursuing charges against Epstein for sex trafficking and abuse of minors, seeking a potential life sentence. Her efforts were undermined by powerful figures, including Epstein's legal team and possibly higher-ups in the U.S. Attorney's office, leading to a controversial non-prosecution agreement and Epstein's lenient 13-month sentence with work release. Villafaña publicly criticized the deal in a 2011 letter, highlighting interference from influential men who maneuvered to stop her prosecution. Following her resignation from the U.S. Attorney's office, she transitioned to private practice and is currently the Principal of Ann Marie C. Villafaña, P.A., with experience at PRISM Investigations and Examinations LLC in Palm Beach Gardens, Florida. Her involvement in the Epstein case gained renewed attention with her appearance in the 2020 Netflix documentary series 'Jeffrey Epstein: Filthy Rich,' where she provided insights.