The Marcus Foundation is a prominent private family foundation established in 1985 by Bernard "Bernie" Marcus, co-founder of The Home Depot, and his wife, Billi Marcus. Committed to entrepreneurial philanthropy, the foundation focuses on saving and changing lives by supporting initiatives in five key areas: Jewish causes, veterans' support, education, healthcare, and medical research. It has granted over $750 million to various organizations, emphasizing innovative partnerships to address both short-term critical needs and systemic challenges. The foundation particularly prioritizes improving cure rates for childhood brain tumors through direct funding of clinical research and supports other brain-related research areas. Additionally, the foundation provided significant financial support to The Home Depot's expansion. It seeks grantees and partners who bring creative thinking to explore new ventures. Bernard and Billi Marcus have committed to The Giving Pledge, pledging the majority of their wealth to charitable causes. A notable recent contribution includes a $30 million grant in 2025 to the University of Michigan and Stanford University for research benefiting stroke patients. Operating as a 501(c)(3) nonprofit primarily based in Georgia, the foundation aligns with conservative values and continues to influence communities through targeted giving in health, education, and community support.